Clinicals & Literature on Univestin™ UP446, and the anti-inflammatory and analgesic effects of Scutellaria baicalensis & Acacia catechu
A number of studies have been undertaken focussing on the effective properties of Univestin™ UP446 — Cararthron®’s active ingredient — and the anti-inflammatory and analgesic effects of Scutellaria baicalensis & Acacia catechu, concerning their use in the treatment of osteoarthritis.
A selection of these clinical scientific articles, and their abstracts are listed below:
- B.P. Burnett, Q. Jia, Y. Zhao, and R.M. Levy, (2007) A Medicinal Extract of Scutellaria baicalensis and Acacia catechu Acts as a Dual Inhibitor of Cyclooxygenase and 5-Lipoxygenase to Reduce Inflammation. Journal of Medicinal Food.
- B.P. Burnett, S. Silva, M.H. Mesches, S. Wilson, Q. Jia, Safety Evaluation of a Combination, Defined Extract of Scutellaria baicalensis and Acacia catechu
- B.P. Burnett, Y. Zhao, Q. Jia, M.H. Mesches, A Combination of Free-B-Ring Flavonoid and Flavan, Anti-Inflammatory Plant Extract Maintains Memory and Speed of Processing in Animal and Human Clinical Models
- R.M. Levy, R. Saikovsky, E. Shmidt, A. Khokhlov, B.P. Burnett, (2009) Flavocoxid is as effective as naproxen for managing the signs and symptoms of osteoarthritis of the knee in humans: a short-term randomized, double-blind pilot study, Nutrition Research Journal
- Sampalis, J & Brownell, LA. A randomized, double blind, placebo and active comparator controlled pilot study of UP446, a novel dual pathway inhibitor anti-inflammatory agent of botanical origin. Nutrition Journal 2012, 11:21 doi:10.1186/1475-2891-11-21